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Only 5% of white women and 0.6% of black women are potential candidates for tamoxifen chemoprevention.
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The FDA has approved Pfizer's eplerenone (Inspra) for the treatment of congestive heart failure (CHF) in patients who have sustained a myocardial infarction.
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Although vasculitic diseases generally are uncommon in the pediatric population, early recognition of processes that do occur is important to prevent sequelae. The authors provide a comprehensive review of the most common vasculitic diseases in children, with an emphasis on diagnostic clinical features, key laboratory studies, and appropriate therapy.
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This is the first study to examine whether nuclear transfer stem cells are effective in an animal model of Parkinsons disease. Nuclear transfer is a means of creating stem cells that are genetically identical to the donor.
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West Nile virus may present as meningitis, encephalitis, meningoencephalomyelitis, and Guillain Barré syndrome. Poliomyelitis, as 2 well-documented cases demonstrate, must also be added to the list.
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Helmstaedter and colleagues addressed the question of whether temporal lobe epilepsy may be associated with cognitive decline.
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Deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus is an effective procedure that markedly improves quality of life in patients with medication-refractory essential tremor. An initial wave of enthusiasm greeted the approval of DBS, but concerns have been raised about its long-term efficacy and the risks of hardware failure and infection. To address these questions, a consortium of neurologists set out to enroll patients in a longitudinal clinical trial with long-term follow-up.
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Crowther and associates reported the results of a prospective, randomized, controlled study of the use of 2 intensities of warfarin anticoagulation for prevention of thrombosis in patients with the antiphospholipid antibody syndrome who had previous thrombosis.